Imu-Max is a children’s formula containing two key botanicals
that strengthen antioxidant reserves and support the
immune system in fending off challenges. Used in Israel as an
over-the-counter medicine, Imu-Max contains echinacea,
one of the best-known botanical supplements used to boost
the immune system, and propolis, a product of bee resin,
which helps balance microbial activity and supports healthy
inflammatory balance . This convenient liquid supplement
contains a 300 mg standardized Echinacea angustifolia and
purpurea blend plus 150 mg propolis and vitamin C in a
delicious berry flavor.
The human immune system is a complex network of millions
of immune cells, which act together to protect the body
from constant exposure to threats from our environment. In
most cases, the immune system does a great job of keeping
people healthy, but during certain times of the year or times
of stress, the immune system may require additional support.
Abundant studies have shown the active ingredients in ImuMax
to be especially supportive to the immune system. Active
polysaccharides and polyphenols provide immediate support
for immune challenges, promote healthy inflammatory
balance and provide extra antioxidant protection.
Research has demonstrated the ability of Imu-Max to protect
the immunity of children in the winter months. A double-blind,
placebo-controlled study was carried out on the efficacy of
Imu-Max in a large group of children during a 12-week winter
season. In a group of 430 children ages one to five, 215 children
were given Imu-Max and 215 were given a placebo. Of the
328 children who completed the study, those in the Imu-Max
group experienced a decrease in upper respiratory challenges,
as well as a decrease in the duration. Children in the ImuMax
group also had fewer days absent from day care, fewer
unscheduled physician visits and a significant improvement in
throat irritations and general immune response.
Propolis is a resinous substance collected by bees to seal
their hives and has traditionally been used in folk medicine
since ancient times. Propolis extract has been found to
have microbial balancing activity. [2,3] A recent review found
the key active ingredients in propolis include caffeic acid
phenethyl ester (CAPE) and artepillin C, which modulate the
immune system by suppressing T lymphocytes and activating
macrophage function. In a study examining the effect of
propolis on 50 people, the duration of upper respiratory
symptoms was 2.5 times shorter in the control versus the
placebo group. Propolis has also been shown to support
immune response in mice exposed to a considerable amount
of stress.  Propolis contains over 300 natural compounds such
as polyphenols, antioxidants and amino acids, which exhibit
a broad spectrum of biological support including microbialbalancing,
liver-heart- and brain-protective qualities, along
with promoting healthy inflammatory balance. 
Echinacea species are perennial plants native to Midwestern
North America. In Native American medicine, echinacea was
used more than any other plant for its wide range of applications,
including promoting immune strength and supporting
healthy inflammatory balance. Echinacea is a botanical that
has been extensively studied, and validated in its healthpromoting
properties. An analysis of data from a randomized,
double-blind, placebo-controlled trial of Echinacea purpurea in 524 children, ages 2 to 11, found that those given echinacea
demonstrated improved immune response and reduction in
upper respiratory challenges, compared to those receiving
placebo. A meta-analysis of three studies examining the
efficacy of echinacea extracts in preventing the development
of seasonal immune challenges found that those given
echinacea showed a significant improvement in markers of
immunity, versus children given a placebo. An additional
randomized, double- blind study found that treatment with
echinacea at onset of upper respiratory challenge supported
immune response in a much faster period of time versus
placebo.  The botanical has also been found to promote
microbial balance when supplemented prophylactically. 
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and Vitamin C in Preventing Respiratory Tract Infections in
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2. PDR Health. www.pdrhealth.com Propolis.
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