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L-Glutamine is the most abundant “free” amino acid in the body. L-Glutamine is found in higher concentration than other proteins (amino acids) in vital tissues such as the brain, intestinal mucosa cells, immune cells, skeletal and smooth muscle. In muscle, the concentration of free glutamine appears to influence whether muscles will be broken down (catabolism – low glutamine content) or built up (anabolism – high glutamine content). The reason is that when the catabolic hormone cortisol attaches to its receptor it stimulates an enzyme called glutamine synthetase to break down muscle tissue, which in turn releases glutamine. The end result is a reduction in muscle mass. Maintaining high blood levels of glutamine inactivates glutamine synthetase so your body does not tear down muscle tissue.
Glutamine is also known as a Nitrogen shuttle, a substance that picks up and drops off nitrogen around the body. Nitrogen is an essential component of DNA, the genetic material of life and muscle building. Glutamine is a prominent contributor to the functional integrity of the intestines and serves as an energy source for these high activity cells.* In the cells of the immune system, glutamine is pivotal in their response to “foreign” challenges by serving both as metabolic fuel and as a precursor to RNA and DNA.* Glutamine is the dominant amino acid in cerebrospinal fluid and readily enters the brain where it can serve as a precursor to neurotransmitters. Glutamine is readily absorbed from the intestinal tract and has a mild sweet taste. MRM’s L-Glutamine is produced through fermentation by Japan’s leading pharmaceutical production facility. It is not synthetically produced.
Serving Size:1 Scoop
Glutamine is a glucogenic (glucose creating), nonessential amino acid that has multiple roles in the body. Glutamine is synthesized mainly in skeletal muscle and the liver and acts as a “nitrogen shuttle” between organs, a fuel for cells of the immune system and intestines, and a precursor for nucleotide synthesis.
Glutamine is also a powerful cell volumizer. An increase in cell volume, also called cell swelling, stimulates anabolic pathways (synthesis of proteins and glycogen) and inhibits catabolic pathways (protein degradation).
Recent findings suggest that glutamine content in skeletal muscle and other tissues appears to have a regulatory role in whole body protein synthesis. Glutamine levels inside muscle govern protein synthesis and nitrogen balance and therefore support muscle growth.
During times of stress, such as exercise, glutamine levels in the skeletal muscle are depleted. This glutamine released from skeletal muscle is derived from muscle proteins, the intramuscular free amino acid pool, and newly synthesized glutamine. The newly synthesized glutamine is created by using BCAAs obtained from muscle protein breakdown. Restoring glutamine levels after exercise is vital to recovery and recuperation.