In a study, the combination of glucosamine HCl, chondroitin sulfate and manganese ascorbate demonstrated the ability to promote joint function. The combination of glucosamine and chondroitin may also provide support for healthy hyaluronic acid content and synovial fluid. The trace mineral manganese plays a key role in supporting glycosaminoglycan and mucopolysaccharide production and encourages the antioxidant activity of superoxide dismutase. Vitamin C, as ascorbate, is a vital nutrient for proper collagen formation and also serves as an antioxidant.‡