DESCRIPTION
Douglas Laboratories® is proud to introduce Ultra Preventive® 2 Daily tablets with important vitamins and
minerals plus powerful antioxidant support from a proprietary phytonutrient blend of standardized spinach,
blueberry and strawberry extracts, carotenoids, and methylated resveratrol in just 2 easy-to-swallow tablets
daily. Astaxanthin is included as the most powerful carotenoid antioxidant for healthy aging.† Activated forms
of B vitamins in Ultra Preventive® 2 Daily ensure proper utilization of vitamins.
FUNCTIONS
Studies show that a high percentage of adults in North America and other developed areas eat less than the
minimum daily allowance of 10 or more essential nutrients. Adequate amounts and proper balance of these
nutrients are needed not only for maintaining good health, but also for the dietary management of the body’s
structure as well as the optimum functioning of its various systems, including the immune and gastrointestinal
systems.
Ultra Preventive® 2 Daily has been carefully developed to contain the right proportions of vitamins, minerals,
trace elements, and other nutrients without danger of toxic build-up or other side effects. Each ingredient is
selected in consideration of its absorbability, competitive relationship with other nutrients, allergenic potential,
and long-term safety. Certain nutrients such as beta-carotene, vitamin D, and B-complex vitamins are included
in high-potency amounts because of the vital roles they play in antioxidant protection, energy production, the
maintenance of healthy blood cells, the nervous system, hormonal balance, and more. Minerals and trace
elements are provided in their safest and most bioavailable forms.
Ultra Preventive® 2 Daily contains Metafolin®, a patented, natural form of (6S) 5-methyltetrahydrofolate (5-
MTHF). L-methylfolate is the naturally occurring, predominant form of folate commonly found in cells and is
essential for overall health, as it participates as a cofactor in a reaction that involves the remethylation of
homocysteine to methionine. Unlike synthetic folic acid, L-methylfolate can be used directly by the body,
without the need for an additional conversion via the enzyme (5, 10 methylenetetrahydrofolate reductase
(MTHFR)). In certain populations, the body’s ability to convert folic acid to 5-MTHF by use of this enzyme may
be compromised due to genetic differences. Metafolin® contains only the S isomer of 5-MTHF and has been
shown to be the only form of folate to be able to cross the blood-brain barrier.
Ultra Preventive® 2 Daily also includes important phytonutrients in a proprietary blend of wild blueberry,
strawberry and spinach extracts to supply active polyphenols for protection against free radical damage.
Lutein, lycopene, zeaxanthin, and astaxanthin are carotenoid antioxidants for ocular health and beyond.
Astanxanthin, the most powerful carotenoid sourced from algae, is increasingly popular due to its’ numerous
health benefits studied such as cardiovascular, and immune support. † Pterostilbene, a methylated form of
resveratrol is considered the next generation of resveratrol. Pterostilbene has advantages over resveratrol:
superior biological activity, better oral bioavailability, and slower metabolism in the body. As another potent
antioxidant, pterostilbene has been clinically studied for cardiovascular, blood sugar, cognitive and longevity
support. †
INDICATIONS
Ultra Preventive® 2 Daily tablets may be a useful dietary supplement for those who wish to consume the
essential nutrients for health and aging support in 2 easy-to-swallow tablets daily.†
SUGGESTED USE
Adults take 2 tablets daily with food or as directed by a healthcare professional.
SIDE EFFECTS
No adverse effects have been reported.
STORAGE
Store in a cool, dry place, away from direct light. Keep out of reach of children.
REFERENCES
O. Hasselwander, W. Hönlein, L. Schweillert, K. Krömer (2000): 5-Methyltetrahydrofolate: The active form of
folic acid. Functional foods 2000.
Izet M, et al. Cancer Chemother Pharmacol. 2010. Nov 30. [Pterostilbene].
Joseph JA, et al. J. Agric. Food Chem. 56, 10544 (2008). [Pterostilbene].
Jian-Ping Yuan, et al. Molecular Nutrition & Food Research. Jan 2011, Vol. 55, No. 1: 150-165. [Astaxanthin].
Robert G Fassett, Jeff S Coombes. Future Cardiology. Jul 2009, Vol. 5, No. 4: 333-342. [Astaxanthin].
Choi HD, Youn YK, Shin WG. Plant Foods Hum Nutr. 2011 Nov;66(4):363-9. [Astaxanthin].
Ward E. Nutr J. 2014 Jul 15;13:72. [Vitamins and minerals].
Prietl B, Treiber G, Pieber TR, Amrein K.Nutrients. 2013 Jul 5;5(7):2502-21. [Vitamin D].
Klaus-Helge Ibs and Lothar Rink. J. Nutr. 133: 1452S–1456S, 2003. [Zinc].
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Ciccone MM, et al. Mediators Inflamm. 2013;2013:782137. [Carotenoids].
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Kräutler B. Subcell Biochem. 2012;56:323-46. [Vitamin B-12].
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Das UN. Nutrition. 2015 Feb;31(2):283-291. doi: 10.1016/j.nut.2014.08.011. Epub 2014 Sep 4.
Morris MS. Adv Nutr. 2012 Nov 1;3(6):801-12. doi: 10.3945/an.112.002535. [B-vitamins].
Jacobs AM, Cheng D. Rev Neurol Dis. 2011;8(1-2):39-47. [L-methylfolate, methylcobalamin, and pyridoxal 5'-
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Patrick L. Altern Med Rev 2008;13:116-27. [Iodine].
Shukitt-Hale B, Lau FC, Joseph JA. J Agric Food Chem. 2008 Feb 13;56(3):636-41. doi: 10.1021/jf072505f.
Epub 2008 Jan 23. Review. [Strawberry and blueberry].
