Natranix is an alcohol-free, great-tasting syrup formulated
from natural botanicals, made to support respiratory health
and boost children’s immune function during seasonal
challenges. This unique formula includes: Echinacea, for its
role in immune support; thyme, which helps balance mucus
production; sage, for its soothing effect on lung tissue;
elderberry, for its role in managing bronchial secretions and
promoting immunity; and anise, to help loosen and expel
The human immune system is a complex network of millions
of immune cells, which act together to protect the body from
constant exposure to outside invaders. Most of the time, the
immune system does a great job of keeping people healthy,
but during certain times of the year, the immune system may
require additional support. Studies have shown key ingredients
in Natranix to be especially supportive to the immune system,
as they include compounds that support respiratory health
and normal mucus production, offering immediate support
for children and adult immune challenges.
Research has shown echinacea to be beneficial for various
aspects of immune health, including balancing microbial
activity and pro-inflammatory cytokines. A review of
placebo-controlled randomized trials of echinacea found
benefits for early stage upper respiratory tract support. An
herbal compound containing Echinacea angustifolia was
found to enhance respiratory health by 77% among children,
over a one month period. Another research group found an
echinacea product offered dual action for microbial balance
in the respiratory tract and helped promote normal levels of
Thyme has a long history of use in natural medicine in
connection with chest and respiratory support. The health
supporting effects of Thymol, its primary volatile oil, are welldocumented.
Thyme and its extracts have been found to relax
respiratory muscles  and and to possess microbial balancing
properties.[6,7] Thyme has also been shown to help increase the
transport of mucus by cilia (minute, hair-like structures in the
lungs that help expel mucus out of the lungs).
Elderberry has been used for centuries to support upper
respiratory health. Elderberry fruit preparations have been
shown to provide antioxidant support and microbial balancing
effects in vitro,  and has been shown to have balancing
effects across a broad range of microbial organisms. One
randomized, double-blind, placebo-controlled study done in
Norway, investigated the efficacy and safety of oral elderberry
syrup among 60 patients aged 18-54 years, with upper
respiratory symptoms for 48 hours or less. They received 15
ml of elderberry or placebo syrup 4 times a day for 5 days,
and symptoms were recorded using a visual analogue scale.
Elderberry boosted immune function and calmed respiratory
challenges on an average of four days earlier than the placebo
Sage or Salvia officinalis is approved by the German Commission
E for external use in supporting the mucous membranes of the mouth and throat. The botanical has been used historically
to promote a healthy respiratory tract, gastrointestinal tract,
mouth and skin. Studies have repeatedly shown it to possess
microbial balancing effects. [12,13]
1. Sharma M, Anderson SA, Schoop R, Hudson JB. Induction
of multiple pro-inflammatory cytokines by respiratory
viruses and reversal by standardized Echinacea, a potent
antiviral herbal extract. Antiviral Res. 2009 Aug;83(2):165-
2. Barrett B, Vohmann M, Calabrese C. Echinacea for upper
respiratory infection. J Fam Pract. 1999 Aug;48(8):628-35.
3. Minetti AM, Forti S, Tassone G, Torretta S, Pignataro L.
Efficacy of complex herbal compound of Echinacea
angustifolia (Imoviral® Junior) in recurrent upper respiratory
tract infections during pediatric age: preliminary results.
Minerva Pediatr. 2011 Jun;63(3):177-82.
4. Sharma SM, Anderson M, Schoop SR, Hudson JB.
Bactericidal and anti-inflammatory properties of a
standardized Echinacea extract (Echinaforce): dual actions
against respiratory bacteria. Phytomedicine 2010 Jul;17(8-
9):563-8. Epub 2009 Dec 29.
5. Engelbertz J, Lechtenberg M, Studt L, Hensel A, Verspohl
EJ. Bioassay-guided fractionation of a thymol-deprived
hydrophilic thyme extract and its antispasmodic effect. J
Ethnopharmacol. 2012 Jun 14;141(3):848-53.
6. Sienkiewicz M, Lysakowska M, Ciecwierz J, Denys P,
Kowalczyk E. Antibacterial activity of thyme and lavender
essential oils. Med Chem. 2011 Nov;7(6):674-89.
7. Sienkiewicz M, Lysakowska M, Denys P, Kowalczyk E. The
antimicrobial activity of thyme essential oil against
multidrug resistant clinical bacterial strains. Microb Drug
Resist. 2012 Apr;18(2):137-48. Epub 2011 Nov 21.
8. Begrow F, Engelbertz J, Feistel B, Lehnfeld R, Bauer K,
Verspohl EJ. Impact of thymol in thyme extracts on their
antispasmodic action and ciliary clearance. Planta Med.
2010 Mar;76(4):311-8. Epub 2009 Oct 6.
9. Vlachojannis JE, Cameron M, Chrubasik S. A systematic
review on the sambuci fructus effect and efficacy profiles.
Phytother Res. 2010 Jan;24(1):1-8.
10. Krawitz C, Mraheil MA, Stein M, Imirzalioglu C, Domann
E, Pleschka S, Hain T. Inhibitory activity of a standardized
elderberry liquid extract against clinically-relevant human
respiratory bacterial pathogens and influenza A and B
viruses. BMC Complement Altern Med. 2011 Feb 25;11:16.
11. Zakay-Rones Z1, Thom E, Wollan T, Wadstein J.
Randomized study of the efficacy and safety of oral
elderberry extract in the treatment of influenza A and B
virus infections. J Int Med Res. 2004 Mar-Apr;32(2):132-40.
12. Bouajaj S, Benyamna A, Bouamama H, Romane A,
Falconieri D, Piras A, Marongiu B. Antibacterial, allelopathic
and antioxidant activities of essential oil of Salvia officinalis
L. growing wild in the Atlas Mountains of Morocco. Nat
Prod Res. 2013;27(18):1673-6.
13. Stefanovic OD1, Stanojevic DD, Comic LR. Synergistic
antibacterial activity of Salvia officinalis and Cichorium
intybus extracts and antibiotics. Acta Pol Pharm. 2012 MayJun;69(3):457-63.