L-glutamine is an amino acid which serves as a primary source of fuel for the small intestines. Epithelial cells in the small intestines (enterocytes) use L-glutamine as their metabolic fuel which helps maintain mucosal growth, structure, and function. In times of stress, L-glutamine has been shown to become a conditionally essential amino acid, helping to regenerate and maintain a healthy mucosal barrier.
Gamma oryzanol is a natural component of rice bran oil. It is a mixture of ferulic acid esters of sterol and triterpene alcohols. Rice bran oil includes about 1-2% gamma oryzanol, which functions as a highly effective antioxidant in the GI tract.
N-acetyl glucosamine is the acetylated form of glucosamine. N-acetyl glucosamine is a mucin precursor and has been shown to increase the production of mucus within the GI tract.
Lactoferrin is a glycoprotein that is naturally found in colostrum, a milky fluid produced by the mammary glands. Lactoferrin plays a major role in supporting immune health including both innate and adaptive immune functions. Lactoferrin helps support microbial and inflammatory balance.
Silymarin (Milk Thistle Seed Extract)
Milk thistle (Silybum marianum) is an annual plant indigenous to Europe and the United States and has been used for centuries as an herbal medicine to support liver health. The extract of milk thistle has silymarin, the biologically active component found in the seeds and leaves of this plant. Silymarin provides liver- protective effects via several mechanisms of action, including inhibiting lipid peroxidation; supporting liver detoxification through enhancement of the liver’s glucuronidation pathways; and protection against glutathione depletion.
N-acetyl cysteine (NAC) is a sulfyhydryl containing amino acid that is commonly used to support liver and gut health. NAC is an effective precursor to the major antioxidant in the body, glutathione. Oral supplementation with NAC has been shown to increase intracellular glutathione levels.
Mucosagen includes the synergistic nutrient combination of zinc, vitamin A, and biotin, which are crucial form maintaining GI health. Zinc is an essential mineral that is widely recognized for its role in gut and immune health. Zinc has been shown to strengthen GI barrier function by supporting the structure of tight junctions. Vitamin A is crucial for supporting GI integrity, promoting inflammatory balance by reducing NFkB, and supporting mucus production. Biotin is an essential nutrient that is produced by several species of intestinal bacteria. Biotin deficiency is often present in individuals with GI challenges.