Lipitrol by Ortho molecular Products
- Promotes Healthy Cholesterol Levels
- Supports the Body’s Natural Cholesterol Removal Pathways
- Provides Antioxidant Support to Protect Blood Vessels
- Helps Maintain Optimal Cardiometabolic Health
Lipitrol includes nutrients that work in synergy to support healthy blood fats and maintain healthy cholesterol levels. The blend of ingredients in Lipitrol enhances the body’s natural cholesterol removal process by increasing the formation of bile and helping the liver to obtain more cholesterol from the serum.
Sytrinol, one of Lipitrol’s key ingredients, is a potent blend of polymethoxylated flavones, citrus flavonoids, and tocotrienols from palm fruit extract. All of these ingredients help to support cholesterol metabolism, provide antioxidant benefits, and maintain a balanced inflammatory response.
Other key ingredients include 200 mg of chromium as a patented chromiumniacin complex, 500 mg of gugul (2.5% gugulsterones), and 150 mg of artichoke leaf extract. Guar gum, a unique fiber, is also included to help bind bile in the GI tract, ensuring full cholesterol excretion.
Cholesterol is made soluble by bile acids, which help to enhance
the digestion and absorption of dietary fats, making bile one
of the major routes for the elimination of dietary cholesterol
from the body. Ingested as part of the diet or derived from
synthesis in the liver, cholesterol, together with bile acids, is
conjugated to an amino acid and actively secreted into the GI
tract. Lipitrol increases the production of bile, working with
the body’s natural process of cholesterol elimination.
Sytrinol® promotes healthy cholesterol metabolism by
helping to control the degradation rate of the HMG-CoA
reductase enzyme (required for cholesterol synthesis).
Sytrinol®’s proprietary nutrient blend includes PMFs, unique
citrus flavonoids (tangeretin, hesperidin and naringin), that
inhibit the hepatic synthesis of cholesterol “building blocks,”
apolipoprotein B and triglycerides. PMFs also help to maintain
normal levels of inflammation, and offer extra antioxidant
support to protect blood vessels and prevent cholesterol
oxidation; both essential for cardiometabolic health. In
addition, the tocotrienols in Sytrinol® limit the activity of
HMG-CoA reductase by decreasing the half-life of this enzyme,
helping to maintain balanced cholesterol levels without
unwanted side effects.
Sytrinol®’s effects have been shown
in a variety of studies, including several human intervention
trials. A 12-week, placebo-controlled clinical trial involving 120
men and women showed that compared to placebo, patients
receiving Sytrinol® had significantly improved cardiovascular
parameters. Those taking Sytrinol® had significantly improved
markers of blood fats, and maintained healthy cholesterol
levels. Other studies using PMFs including tangeretin,
hesperetin, also found them to support healthy blood fat
and cholesterol levels.[2-6] PMFs have also been shown in the
literature to support healthy blood sugar metabolism.
Gugul, a resin produced by the stem of the Commiphora
mukul tree, has active components called gugulsterones,
which support liver cholesterol metabolism and improve
cholesterol uptake from bile. Several small studies have
shown gugulipids to support the maintenance of normal
cholesterol levels and support blood fat balance in humans.[8-10]
Proposed mechanisms for gugul’s lipid-lowering effect
includes increasing LDL receptors on liver cells allowing more
cholesterol to be pulled from the blood stream.
Artichoke Leaf Extract†
Artichoke leaf extract (ALE) is known as a choloretic, and
has specific compounds that promote the liver’s cholesterol
reserves. Cynarin, a key constituent of ALE, also supports the
production and release of bile, the main transport mechanism
of dietary cholesterol from the body. ALE has been shown to
reduce of HMG-CoA reductase enzyme, even when stimulated
by insulin. Several key studies have also shown cynarin to be
useful in supporting healthy cholesterol levels.[13,14]
A randomized, double-blind, placebo-controlled study
investigating the effects of eight weeks of ALE supplementation
or placebo found ALE to significantly modulate
Research has shown chromium to be particularly beneficial
for optimal carbohydrate and lipid metabolism. Lipitrol uses
a well-researched, niacin-bound chromium complex known
as ChromeMate®. This unique form of chromium has been
shown enhance glucose tolerance factor (GTF), the biologically
active form of chromium in the body which works closely
with insulin to facilitate the uptake of glucose into cells. In
this way, it helps maintain normal sugar levels, especially
among those with less than adequate intake and those with
greater consumption of refined foods. In a study examining
the benefits of ChromeMate®, healthy cholesterol levels were
better maintained among men who took this unique GTFenhancing
Soluble fibers, especially guar gum, have been shown to
assist in maintaining normal cholesterol by sequestering the
cholesterol-laden bile, ensuring full excretion out of
2 capsules per day or as recommended by your health
care professional. For best results, consult your health care
professional about using Fiber Plus with Lipitrol.
Does Not Contain
Gluten, yeast, artificial colors and flavors.
Do not consume this product if you are pregnant or nursing.
Consult your physician for further information.
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primary cultured rat hepatocytes by artichoke (Cynara
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application of cynarin in the treatment of hyperlipemic
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