1. Gamma E Tocopherol / Tocotrienol by Life Extension 60 Softgels

Gamma E Tocopherol / Tocotrienol by Life Extension 60 Softgels
Gamma E Tocopherol / Tocotrienol by Life Extension

Gamma E Tocopherol / Tocotrienol by Life Extension 60 Softgels

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Gamma E Tocopherol / Tocotrienol by Life Extension
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Gamma E Mixed Tocopherols & Tocotrienols is an all-natural, oral formula that provides a full spectrum vitamin E for potent antioxidant protection. The term "vitamin E" refers to a family of eight related, lipid-soluble, antioxidant compounds widely present in plants. The tocopherol and tocotrienol subfamilies are each composed of alpha, beta, gamma, and delta fractions having unique biological effects. Gamma E Mixed Tocopherols & Tocotrienols contains the complete spectrum of all eight vitamin E tocopherol and tocotrienol forms.

Benefits at a Glance

  • Full spectrum vitamin E
  • Potent antioxidant protection
  • Provides both members of the vitamin E family — tocopherols and tocotrienols
  • Provides the optimal amount and ratio of alpha, beta, gamma, and delta sub-families

Vitamin E is a Family of Antioxidant Compounds

The term "vitamin E" refers to a family of eight related, lipid-soluble, antioxidant compounds widely present in plants. The tocopherol and tocotrienol subfamilies are each composed of alpha, beta, gamma, and delta fractions having unique biological effects.

Different ratios of these compounds are found in different parts of a plant. For example, the green parts of a plant contain mostly alpha tocopherol and the seed germ and bran contain mostly tocotrienols.

Along with other nutrients, tocopherols and tocotrienols are concentrated in the bran layers of the rye grain, and are only present at low levels in the flour endosperm. Tocopherols are also present in algae, mint teas, and other foods.1-4

Vitamin E Provides Potent Antioxidant Benefits

As a family of antioxidant compounds, vitamin E is one of the most researched and most important nutrients to consume daily. One or more members of the vitamin E family may:

  • Maintain cell membrane integrity and reduce cellular aging5-7
  • Act as a free radical scavenger8-11
  • Maintain healthy platelet aggregation12-15
  • Promote a healthy nervous system and retina of the eye16-19
  • Maintain healthy cognitive function20-25
  • Enhance immune function26-29

Gamma Tocopherol is Critically Important

Prestigious scientific journals have highlighted gamma tocopherol as one of the most critically important forms of vitamin E for those seeking optimal health benefits. In fact, studies show the combination of alpha- and gamma-tocopherol supplementation appears to be superior to either supplementation alone on biomarkers of oxidative stress and on inflammatory factors.30, 31

Most commercial vitamin E supplements contain little, if any, gamma tocopherol. They instead rely on alpha tocopherol as the primary ingredient. However, it is gamma tocopherol (not the alpha form) that quenches peroxynitrite, the free radical that plays a major role in the development of age-related decline.32

Tocotrienols Support Arteries and Nerves

Tocotrienols have shown superior action in maintaining arterial health.33-36 In 2010, a team of Asian scientists demonstrated that this class of nutrients, which are difficult to obtain in sufficient quantities through dietary sources alone, may provide superior support in maintaining triglyceride levels already within healthy range in aging individuals.

Just 120 mg per day of gamma-delta tocotrienols (provided in 3-4 softgels) induced a 28% decline in triglyceride levels in the blood after just one month. This wonder nutrient is so effective because of its structure of double bonds in the isoprenoid side chain, making it a great scavenger of free radicals.37

Research has shown that tocotrienols display potent neuroprotective properties and in particular alpha-tocotrienol is being touted as the most potent neuroprotective form of vitamin E.38-42

References

  1. Proc Nutr Soc. 2003 Feb;62(1):117-22.
  2. J Chromatogr A. 2004 Oct 29;1054(1-2):227-33.
  3. Nahrung. 2004 Feb;48(1):34-7.
  4. J Am Diet Assoc. 1979 Dec;75(6):647-65.
  5. Clinics (Sao Paulo). 2012;67(2):135-43.
  6. Oxid Med Cell Longev. 2012;2012:785743.
  7. J Vasc Surg. 2004 Jan;39(1):229-37.
  8. Diabetes Metab Res Rev. 2007 Oct;23(7):539-46
  9. Antioxid Redox Signal. 2002 Oct;4(5):791-8.
  10. Biol Chem. 2002 Mar-Apr;383(3-4):457-65.
  11. J Nutr. 2001 Feb;131(2):366S-368S.
  12. J Nutr. 2001 Feb;131(2):374S-377S.
  13. Circulation. 2007 Sep 25;116(13):1497-503.
  14. Asia Pac J Clin Nutr. 2007;16(3):422-8.
  15. Haematologica. 2002 Apr;87(4):420-6.
  16. J Am Coll Nutr. 2004 Jun;23(3):233-8.
  17. Fundam Clin Pharmacol. 2003 Dec;17(6):703-7.
  18. J Neurosci Res. 2004 Mar 15;75(6):845-53.
  19. Curr Eye Res. 2010 Sep;35(9):842-9.
  20. Neurobiol Aging. 2002 Sep-Oct;23(5):737-45.
  21. Alzheimers Dement. 2008 May;4(3):223-7.
  22. J Nutr Health Aging. 2002;6(6):392-404.
  23. Brain Res. 2001 Feb 16;892(1):211-7.
  24. Iran Biomed J. 2008 Oct;12(4):217-22.
  25. Toxicology. 2003 Jul 15;189(1-2):129-46.
  26. Br J Cancer. 2003 Jun 16;88(12):1948-55.
  27. Cancer Immunol Immunother. 2007 Jul;56(7):973-84. 
  28. Vitam Horm. 2007;76:393-418.
  29. Zhonghua Yu Fang Yi Xue Za Zhi. 2003 Mar;37(2):112-4.
  30. Eur J Nutr. 2008 Oct;47(7):387-92.
  31. Free Radic Biol Med. 2008 Mar 15;44(6):1203-8.
  32. Proc Natl Acad Sci USA. 1997 Apr 1; 94(7):3217-22.
  33. Atherosclerosis. 2005 May;180(1):19-25.
  34. Ann N Y Acad Sci. 2004 Dec;1031:401-4.
  35. Arch Pharm Res. 2008 Sep;31(9):1212-7.
  36. Clinics (Sao Paulo). 2009;64(3):235-44.
  37. Free Radic Biol Med. 2011 Sep 15;51(6):1164-74.
  38. Wei Sheng Yan Jiu. 2004 Mar;33(2):243-5.
  39. Mol Aspects Med. 2007 Oct-Dec;28(5-6):692-728.
  40. Neuropharmacology. 2004 Nov;47(6):904-15.
  41. Indian J Exp Biol. 2011 Oct;49(10):732-8.
  42. Semin Urol Oncol. 1999 May;17(2):85-90.151

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